ImmuneFx Cancer Vaccine
The purpose of a cancer vaccine is to initiate and focus the enormous power of the immune system on the destruction of tumor cells. Our cancer vaccine technology, which we call ImmuneFx (IFx), does this in the most effective manner possible. By expressing a bacterial antigen on the surface of a patient’s own tumor cells, IFx primes and educates the immune system to destroy tumor cells throughout the body without harming healthy cells and tissues. Our IFx-Hu2.0 vaccine is currently being tested in a Phase I clinical trial for Stage III/IV unresectable cutaneous melanoma.
Simple, yet powerful, IFx combines cell AND gene therapy to provide a universal solution for personalized results.
The power of IFx has been demonstrated through the >3,000 doses administered so far to veterinary patients with naturally occurring cancers. Data accrued from 430 companion animals, some 126 breeds with 44 different types of cancer, have much more predictive value for what will happen when administered to humans than any experimentally induced laboratory mouse model ever could. With minimal side-effects and a strong correlation between clinical efficacy and immune response, IFx has proven its ability to prime and present the complete repertoire of tumor antigens to the immune system in such a way that evokes a broad spectrum of immune response including both innate and adaptive immunity.
IFx is a true multi-indication cancer vaccine that effectively combines cell and gene therapy to mobilize multiple components of the innate and adaptive immune systems that target the entire antigenic repertoire of heterologous tumors by maximizing antigen presentation and inter-antigenic epitope spreading in a clinically relevant manner.
2019 August 13